A branch point of Streptomyces sulfur amino acid metabolism 1 controls the production of albomycin
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چکیده
7 a Department of Biological Sciences, Ohio University, Athens, OH 45701, USA 8 b Department of Pharmaceutical Sciences, University of Kentucky College of Pharmacy, 9 Lexington, KY 40536, USA 10 c Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin 11 University, Tianjin 300072, P.R. China 12 13 *Address Correspondence to Shawn Chen, [email protected] 14 15 16 Running title: Improved albomycin production of Streptomyces 17 18 19 20 21 22 23 24 25 AEM Accepted Manuscript Posted Online 30 October 2015 Appl. Environ. Microbiol. doi:10.1128/AEM.02517-15 Copyright © 2015, American Society for Microbiology. All Rights Reserved.
منابع مشابه
A Branch Point of Streptomyces Sulfur Amino Acid Metabolism Controls the Production of Albomycin.
Albomycin (ABM), also known as grisein, is a sulfur-containing metabolite produced by Streptomyces griseus ATCC 700974. Genes predicted to be involved in the biosynthesis of ABM and ABM-like molecules are found in the genomes of other actinomycetes. ABM has potent antibacterial activity, and as a result, many attempts have been made to develop ABM into a drug since the last century. Although th...
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تاریخ انتشار 2015